A randomized, phase 1, placebo-controlled trial of APG-157 in oral cancer demonstrates systemic absorption and an inhibitory effect on cytokines and tumor-associated microbes.
Basak, Saroj K. PhD 1; Bera, Alakesh PhD 2; Yoon, Alexander J. MS 3; Morselli, Marco PhD 4; Jeong, Chan BS 1; Tosevska, Anela PhD 4; Dong, Tien S. MD 5; Eklund, Michael BS 2; Russ, Eric BS 2; Nasser, Hassan MD 6; Lagishetty, Venu PhD 5; Guo, Rong MS 7; Sajed, Dipti MD, PhD 8; Mudgal, Sharmila MD, MPH 9; Mehta, Parag PhD 9; Avila, Luis PhD 9; Srivastava, Meera PhD 2; Faull, Kym PhD 3; Jacobs, Jonathan MD, PhD 5; Pellegrini, Matteo PhD 4,10,11; Shin, Daniel Sanghoon MD, PhD 10,12; Srivatsan, Eri S. PhD 1,10,11; Wang, Marilene B. MD *,1,6,10
[Article] Cancer. 126(8):1668-1682, April 15, 2020.

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