IL-6 antagonists to replace systemic corticosteroids as the preferred anti-inflammatory therapy in patients with COVID-19?.
Kow, Chia Siang a,b,*; Zaihan, Abdullah Faiz c; Ramachandram, Dinesh Sangarran b; Hasan, Syed Shahzad d,e
[Miscellaneous]
Cytokine.
149:155730, January 2022.
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HIGHLIGHTS:
* IL-6 antagonists can be an adequate substitute for systemic corticosteroids.
* The use of both IL-6 antagonists and systemic corticosteroids may have synergistic effects.
* Co-administration of systemic corticosteroid and IL-6 antagonists may benefit those with very high IL-6 production.
(C) 2022Elsevier, Inc.