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The taxanes: an update. Crown, John; O'Leary, Michael [Miscellaneous Article] Lancet. 355(9210):1176-1178, April 1, 2000.
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The taxanes are anticancer cytotoxics that stabilise cellular microtubules. Two members, paclitaxel and docetaxel have substantial activity. One or both agents are widely accepted as evidence-based components of therapy for advanced breast, lung, and ovarian carcinomas. Paclitaxel has recently been approved in the USA for the adjuvant treatment of early stage node-positive breast carcinoma.
Copyright. (C) The Lancet Ltd, 2000.