Safety Measures of L-Carnitine L-Tartrate Supplementation in Healthy Men.
RUBIN, MARTYN R.; VOLEK, JEFF S.; GOMEZ, ANA L.; RATAMESS, NICHOLAS A.; FRENCH, DUNCAN N.; SHARMAN, MATTHEW J.; KRAEMER, WILLIAM J.
Journal of Strength & Conditioning Research.
15(4):486-490, November 2001.
The purpose of this investigation was to examine the effects of ingestion of L-CARNIPURE (L-carnitine L-tartrate [LCLT]) on alterations in a complete blood cell profile and in circulating metabolic enzymes. Using a balanced, placebo (P), cross-over design (1 week washout), 10 healthy, active men volunteered and acted as their own control taking either a P or LCLT supplement (3 gday-1) for 3 weeks. Postabsorptive morning blood samples were obtained both before and after 21 days of P and LCLT supplementation. Serum samples were analyzed for clinical chemistries including a complete chemistry panel with markers of liver and renal function along with various minerals and electrolytes. In addition, whole blood was analyzed for a complete blood count with differential. It was determined that there were no statistically significant differences between the LCLT and the placebo conditions for any of the variables examined. The results of this study suggest that LCLT, when used as a dietary supplement, has no adverse effects on metabolic and hemato-logical safety variables in normally healthy en.
(C) 2001 National Strength and Conditioning Association