EVALUATION OF A NEW PERFUSION SOLUTION FOR KIDNEY PRESERVATION.
Johnson, R. W. G.; Anderson, Marilyn; Flear, C. T. G.; Murray, Sheila G. H.; Taylor, R. M. R.; Swinney, John
13(3):270-275, March 1972.
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SUMMARY: We have compared the physical and biochemical properties of plasma and plasma protein fraction (PPF). We have found PPF to be a very satisfactory physiological hepatitis-free plasma substitute. Using PPF as a perfusion solution, we have preserved kidneys for 24 hr after up to 40 min of warm ischaemia and obtained immediate return of function on reimplantation. Perfusion with potassium-enriched plasma protein fraction (PPF2) prevented potassium leakage from the renal cells. Using PPF, we have avoided prefiltration, and we have been able to use a very simple and inexpensive perfusion apparatus.
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