High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity.
Schulz, Manon D. M. 1,12,; Atay, Cigdem 1,12,; Heringer, Jessica J 1,12,; Romrig, Franziska K. F. 1; Schwitalla, Sarah S 1; Aydin, Begum B 2; Ziegler, Paul K. P. 3,4,5; Varga, Julia J 3,4,5; Reindl, Wolfgang W 6; Pommerenke, Claudia C 7; Salinas-Riester, Gabriela G 7; Bock, Andreas A 8; Alpert, Carl C 9,13,+; Blaut, Michael M 9; Polson, Sara C. S. 10; Brandl, Lydia L 11; Kirchner, Thomas T 4,5,11; Greten, Florian R. F. 3,4,5; Polson, Shawn W. S. 10; Arkan, Melek C. M. 1,*
[Letter] Nature. 514(7523):508-512, October 23, 2014.

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: A high-fat diet promotes intestinal tumorigenesis independently of obesity in a mouse model with oncogene activation, by changing the composition of the gut microbiota and altering immune regulation.

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