Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD.
Tramutola, Antonella 1; Triplett, Judy C. 2; Di Domenico, Fabio 1; Niedowicz, Dana M. 3; Murphy, Michael P. 3; Coccia, Raffaella 1; Perluigi, Marzia 1; Butterfield, Allan D. 2,3
Journal of Neurochemistry.
133(5):739-749, June 2015.
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