Double dissociation of spatial impairments and perseveration following selective prefrontal lesions in rats.
Kolb, Bryan; Nonneman, Arthur J.; Singh, R. K.
[Article] Journal of Comparative & Physiological Psychology. 87(4):772-780, October 1974.

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: Reports results of 2 experiments with 27 male Wistar and 27 male hooded Long-Evans rats. Lesions to the medial frontal cortex produced severe deficits on spatial reversal learning and on delayed response, while lesions of the orbital frontal cortex produced perseverative response tendencies on a differential reinforcement of low rates 20-sec schedule and on barpressing extinction. Results are strikingly similar to those resulting from dorsolateral frontal and orbital frontal lesions, respectively, in rhesus monkeys. (24 ref) (PsycINFO Database Record (c) 2006 APA, all rights reserved)

(C) 1974 by the American Psychological Association