Excitation-Contraction Uncoupling: Major Role in Contraction-Induced Muscle Injury.
Warren, Gordon L. 1; Ingalls, Christopher P. 2; Lowe, Dawn A. 3; Armstrong, R. B. 4
Exercise & Sport Sciences Reviews.
29(2):82-87, April 2001.
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WARREN, G.L., C.P. INGALLS, D.A. LOWE, and R.B. ARMSTRONG. Excitation-contraction uncoupling: major role in contraction-induced muscle injury. Exerc. Sports Sci. Rev., Vol. 29, No. 2, pp. 82-87, 2001. The mechanisms that account for the strength loss after contraction-induced muscle injury remain controversial. We present data showing that (1) most of the early strength loss results from a failure of excitation-contraction coupling and (2) a slow loss of contractile protein in the days after injury prolongs the recovery time.
(C) 2001 American College of Sports Medicine