Pre-diagnostic alcohol consumption and breast cancer recurrence and mortality: Results from a prospective cohort with a wide range of variation in alcohol intake.
Holm, Marianne 1,*; Olsen, Anja 1; Christensen, Jane 1; Kroman, Niels T. 2; Bidstrup, Pernille E. 3; Johansen, Christoffer 3; Overvad, Kim 4; Tjnneland, Anne 1[phi]
[Miscellaneous Article]
International Journal Of Cancer.
132(3):686-694, February 1, 2013.
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: The association between pre-diagnostic alcohol consumption and breast cancer recurrence and breast cancer specific mortality was investigated in 1,052 women diagnosed with early breast cancer in a prospective cohort of 29,875 women. Known clinical, lifestyle and socioeconomic risk factors were evaluated and adjusted for in multivariate analysis. We found a modest but significant association between pre-diagnostic alcohol consumption and breast cancer recurrence with a median follow-up of six years after date of diagnosis, both when using baseline measures of alcohol intake (HR, 1.65; 95% CI, 1.02-2.67; >2 units/day vs. <=1 unit/day) and cumulated alcohol intake (HR, 2.02; 95% CI, 1.06-3.85; >40 drinking years vs. 0
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