Immune Thrombocytopenia in Children Less Than 1 Year of Age: A Single-institution 10-year Experience.
Lo, Clara MD *; Wong, Wendy MD *; Glader, Bertil MD, PhD *,+; Jeng, Michael MD *
Journal of Pediatric Hematology/Oncology.
35(5):406-408, July 2013.
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Immune thrombocytopenia (ITP) in children less than one year of age is less well characterized compared to ITP in toddlers and school-age children. We performed a 10-year retrospective review of ITP patients in this age-cohort at our institution. Diagnosis and classification were made according to the 2009 International Working Group criteria. Fourteen infants were identified. Their bleeding scores were Grades 1 to 2 (79%), Grade 3 (22%), Grades 4 to 5 (0%). Eight patients received treatment with a 75% response rate. Three patients (21%) developed chronic ITP. These observations suggest that ITP in very young patients is similar to typical childhood ITP.
(C) 2013 by Lippincott Williams & Wilkins.