FINDINGS ON RETINAL TOPOGRAPHY AND THICKNESS MAPPING IN AGE-RELATED MACULAR DEGENERATION.
GIESER, JON P. MD; MORI, MAREK MS; BLAIR, NORMAN P. MD; SHAHIDI, MAHNAZ PhD
21(4):352-360, August 2001.
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Purpose: To report alterations in the retinal topography and thickness in typical cases of age-related macular degeneration (ARMD).
Methods: An optical imaging system was applied to patients with ARMD with alterations in the retinal structures. The system generates a series of 20 optical section images that encompass a 2 mm x 2 mm retinal area. The optical sections are digitized and analyzed to provide topographic maps of the vitreo-retinal and chorio-retinal surfaces and the retinal thickness.
Results: Retinal topography and thickness mapping in a normal eye corresponded to normal anatomy. Topographic mapping in a patient with confluent drusen indicated elevation of the vitreo-retinal surface. Retinal topography in a patient with retinal pigment epithelium detachment displayed localized elevation of the chorio-retinal surface. The thickness map in a patient with geographic atrophy of the retinal pigment epithelium revealed retinal thinning. In the patients with choroidal neovascularization, the vitreo-retinal and chorio-retinal surfaces were elevated. The chorio-retinal surface map in a patient with evolving disciform scar displayed topographic variations corresponding to the fibrovascular tissue underlying the serous detachment.
Conclusion: Retinal topography and thickness mapping is useful for visualization and evaluation of pathologic alterations in retinal structures due to ARMD.
(C) The Ophthalmic Communications Society, Inc.