Histamine2-Receptor Antagonists: Standard Therapy for Acid-Peptic Diseases.
Feldman, Mark M.D.; Burton, Michael E. Pharm.D.
[Review]
New England Journal of Medicine.
323(25):1749-1755, December 20, 1990.
(Format: HTML, PDF)
: H2 Blockers in Peptic Ulcer Disease
Duodenal Ulcer
All four H2 blockers, when used in the doses shown in Table 1, are capable of healing duodenal ulcer to approximately the same degree.203 204 205 206 207 208 209 210 The average rates of healing with H2 blockers in several placebo-controlled studies among outpatients are shown in Figure 3. The rates of complete healing after two, four, and eight weeks of therapy averaged 51, 78, and 92 percent, all substantially higher than the rates of healing with placebo. It is apparent from Figure 3 that the healing curve for duodenal ulcer may not have reached a plateau after [horizontal ellipsis]
Owned, published, and (C) copyrighted, 1990, by the MASSACHUSETTS MEDICAL SOCIETY
