Definitions and outcome measures for bullous pemphigoid: Recommendations by an international panel of experts.
Murrell, Dedee F. MA, BMBCh, MD, FACD a,*; Daniel, Benjamin S. MBBS a; Joly, Pascal MD, PhD b; Borradori, Luca MD c; Amagai, Masayuki MD, PhD d; Hashimoto, Takashi MD, PhD e; Caux, Frederic MD, PhD f; Marinovic, Branka MD, PhD g; Sinha, Animesh A. MD, PhD h; Hertl, Michael MD i; Bernard, Philippe MD, PhD ae; Sirois, David DMD, PhD j; Cianchini, Giuseppe MD k; Fairley, Janet A. MD m; Jonkman, Marcel F. MD, PhD n; Pandya, Amit G. MD o; Rubenstein, David MD, PhD p; Zillikens, Detlef MD q; Payne, Aimee S. MD, PhD s; Woodley, David MD r; Zambruno, Giovanna MD l; Aoki, Valeria MD, PhD t; Pincelli, Carlo MD u; Diaz, Luis MD p; Hall, Russell P. MD v; Meurer, Michael MD, PhD x; Mascaro, Jose M. Jr. MD y; Schmidt, Enno MD q; Shimizu, Hiroshi MD, PhD w; Zone, John MD z; Swerlick, Robert MD ac; Mimouni, Daniel MD ad; Culton, Donna MD p; Lipozencic, Jasna MD, PhD g; Bince, Benjamin MD aa; Grando, Sergei A. MD, PhD, DSc ag; Bystryn, Jean-Claude MD ab; Werth, Victoria P. MD s,af
[Review]
Journal of the American Academy of Dermatology.
66(3):479-485, March 2012.
(Format: HTML, PDF)
: Our scientific knowledge of bullous pemphigoid (BP) has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in BP. A major obstacle in sharing multicenter-based evidences for therapeutic efforts is the lack of generally accepted definitions for the clinical evaluation of patients with BP. Common terms and end points of BP are needed so that experts in the field can accurately measure and assess disease extent, activity, severity, and therapeutic response, and thus facilitate and advance clinical trials. These recommendations from the International Pemphigoid Committee represent 2 years of collaborative efforts to attain mutually acceptable common definitions for BP and proposes a disease extent score, the BP Disease Area Index. These items should assist in the development of consistent reporting of outcomes in future BP reports and studies.
(C) 2012 by Mosby, Inc.