The following article requires a subscription:



(Format: HTML)

Summary: Twenty-six patients with relapsed or refractory Hodgkin's disease (HD) were treated with an intensive salvage regimen combining ifosfamide (3000 mg/m2/d, days 1-4 through continuous intravenous infusion) and vinorelbine (25 mg/m2, i.v. days 1 and 5) with mesna uroprotection and G-CSF support. Courses were given at 3-week intervals.

Ten patients achieved a complete and 10 patients a partial response, yielding an overall response rate of 77%.The main toxic effect was neutropenia and the combination was well tolerated.

(C) 1998 Blackwell Science Ltd.