Information de reference pour ce titreAccession Number: | 01451458-201409150-00013.
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Author: | Muzny, Christina A. 1; Blackburn, Reaford J. 2; Sinsky, Richard J. 3; Austin, Erika L. 1; Schwebke, Jane R. 1
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Institution: | (1)Division of Infectious Diseases (2)Department of Medicine, University of Alabama at Birmingham (3)Quality, Improvement, and Decision Support, Jefferson County Department of Health, Birmingham, Alabama
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Title: | |
Source: | Clinical Infectious Diseases. 59(6):834-841, September 15, 2014.
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Abstract: | Background. Trichomonas vaginalis (TV) is the most common nonviral sexually transmitted infection (STI) in the world. However, TV is not a reportable STI and, with the exception of HIV-positive women, there are no guidelines for screening in women or men. The objective of this study was to determine the added value of nucleic acid amplification tests (NAATs) for detection of TV in men and women at high risk for infection as well as correlates of infection.
Methods. This was a review of clinical and laboratory data of men and women presenting to the Jefferson County Department of Health Sexually Transmitted Diseases (STD) Clinic and receiving a TV NAAT.
Results. During 2012-2013, 6335 patients (3821 women and 2514 men) received a TV NAAT on endocervical, urethral, or urine specimens. Overall TV prevalence was 20.2%; 27.0% in women and 9.8% in men. Correlates of TV among men included age >40 years, African American race, and >=5 polymorphonuclear cells per high-power field on urethral Gram stain. Age >40 years, African American race, leukorrhea on wet mount, elevated vaginal pH, positive whiff test, and concurrent gonococcal infection were positively associated with TV among women. TV NAAT detected approximately one-third more infections among women than wet mount alone.
Conclusions. TV prevalence among men and women was high in this study, suggesting that both groups should be routinely screened, including those aged >40 years. Improved detection of TV by routine implementation of NAATs should result in better control of this common, treatable STI.
(C) Copyright Oxford University Press 2014.
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Author Keywords: | infectiousness; nucleic acid amplification test; sexually transmitted infection; Trichomonas vaginalis; wet mount.
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References: | 1. World Health Organization. . Global prevalence and incidence of selected curable sexually transmitted infections 2001 Available at: http://www.who.int/hiv/pub/sti/w...- ouverture dans une nouvelle fenêtre Accessed 14 January 2014
2. Cates W Jr. Estimates of the incidence and prevalence of sexually transmitted diseases in the United States. American Social Health Association Panel Sex Transm Dis. 1999;26(suppl 4):S2-7
3. Sutton M, Sternberg M, Koumans EH, et al. The prevalence of Trichomonas vaginalis infection among reproductive-age women in the United States, 2001-2004 Clin Infect Dis. 2007;45:1319-26
4. Ginocchio CC, Chapin K, Smith JS, et al. Prevalence of Trichomonas vaginalis and coinfection with Chlamydia trachomatis and Neisseria gonorrhoeae in the United States as determined by the Aptima Trichomonas vaginalis nucleic acid amplification assay J Clin Microbiol. 2012;50:2601-8
5. Sorvillo F, Smith L, Kerndt P, et al. Trichomonas vaginalis, HIV, and African-Americans Emerg Infect Dis. 2001;7:927-32
6. Sutcliffe S, Newman SB, Hardick A, et al. Prevalence and correlates of Trichomonas vaginalis infection among female US federal prison inmates Sex Transm Dis. 2010;37:585-90
7. Hobbs MM, Kazembe P, Reed AW, et al. Trichomonas vaginalis as a cause of urethritis in Malawian men Sex Transm Dis. 1999;26:381-7
8. Joyner JL, Douglas JM Jr, Ragsdale S. Comparative prevalence of infection with Trichomonas vaginalis among men attending a sexually transmitted diseases clinic Sex Transm Dis. 2000;27:236-40
9. Borchardt KA, al-Haraci S, Maida N. Prevalence of Trichomonas vaginalis in a male sexually transmitted disease clinic population by interview, wet mount microscopy, and the InPouch TV test Genitourin Med. 1995;71:405-6
10. Kaydos-Daniels SC, Miller WC, Hoffman I, et al. The use of specimens from various genitourinary sites in men, to detect Trichomonas vaginalis infection J Infect Dis. 2004;189:1926-31
11. Krieger JN, Jenny C, Verdon M, et al. Clinical manifestations of trichomoniasis in men Ann Intern Med. 1993;118:844-9
12. Gaydos CA, Barnes MR, Quinn N, et al. Trichomonas vaginalis infection in men who submit self-collected penile swabs after internet recruitment Sex Transm Infect. 2013;89:504-8
13. McClelland RS, Sangare L, Hassan WM, et al. Infection with Trichomonas vaginalis increases the risk of HIV-1 acquisition J Infect Dis. 2007;195:698-702
14. Cotch MF, Pastorek JG II, Nugent RP, et al. Trichomonas vaginalis associated with low birth weight and preterm delivery. The Vaginal Infections and Prematurity Study Group Sex Transm Dis. 1997;24:353-60
15. Workowski KA, Berman S;Centers for Disease Control and Prevention. . Sexually transmitted diseases treatment guidelines, 2010 MMWR Recomm Rep. 2010;59:1-110
16. Krieger JN, Tam MR, Stevens CE, et al. Diagnosis of trichomoniasis. Comparison of conventional wet-mount examination with cytologic studies, cultures, and monoclonal antibody staining of direct specimens JAMA. 1988;259:1223-7
17. Huppert JS, Mortensen JE, Reed JL, et al. Rapid antigen testing compares favorably with transcription-mediated amplification assay for the detection of Trichomonas vaginalis in young women Clin Infect Dis. 2007;45:194-8
18. Hobbs MM, Sena AC, Swygard H, et al.Holmes KK, Sparling PF, Stamm WE, et al. Trichomonas vaginalis and trichomoniasis Sexually transmitted diseases. 20084th ed New York McGraw-Hill:771-93
19. Krieger JN, Verdon M, Siegel N, et al. Natural history of urogenital trichomoniasis in men J Urol. 1993;149:1455-8
20. Nye MB, Schwebke JR, Body BA. Comparison of APTIMA Trichomonas vaginalis transcription-mediated amplification to wet mount microscopy, culture, and polymerase chain reaction for diagnosis of trichomoniasis in men and women Am J Obstet Gynecol. 2009;200:188 e1-7
21. Schwebke JR, Hobbs MM, Taylor SN, et al. Molecular testing for Trichomonas vaginalis in women: results from a prospective U.S. clinical trial J Clin Microbiol. 2011;49:4106-11
22. Van Der Pol B, Williams JA, Taylor SN, et al. Trichomonas vaginalis DNA detection using self-obtained vaginal swabs with the BD ProbeTec Qx Assay on the BD Viper System J Clin Microbiol. 2014;52:885-9
23. Bachmann LH, Hobbs MM, Sena AC, et al. Trichomonas vaginalis genital infections: progress and challenges Clin Infect Dis. 2011;53(suppl 3):S160-72
24. Amsel R, Totten PA, Spiegel CA, et al. Nonspecific vaginitis. Diagnostic criteria and microbial and epidemiologic associations Am J Med. 1983;74:14-22
25. Allsworth JE, Ratner JA, Peipert JF. Trichomoniasis and other sexually transmitted infections: results from the 2001-2004 National Health and Nutrition Examination Surveys Sex Transm Dis. 2009;36:738-44
26. Divekar AA, Gogate AS, Shivkar LK, et al. Disease prevalence in women attending the STD clinic in Mumbai (formerly Bombay), India Int J STD AIDS. 2000;11:45-8
27. Lo M, Reid M, Brokenshire M. Epidemiological features of women with trichomoniasis in Auckland sexual health clinics: 1998-99 N Z Med J. 2002;115:U119
28. Swygard H, Sena AC, Hobbs MM, et al. Trichomoniasis: clinical manifestations, diagnosis and management Sex Transm Infect. 2004;80:91-5
29. Garland SM, Tabrizi SN, Chen S, et al. Prevalence of sexually transmitted infections (Neisseria gonorrhoeae, Chlamydia trachomatis, Trichomonas vaginalis, and human papillomavirus) in female attendees of a sexually transmitted diseases clinic in Ulaanbaatar, Mongolia Infect Dis Obstet Gynecol. 2001;9:143-6
30. Meites E, Llata E, Braxton J, et al. Trichomonas vaginalis in selected U.S. sexually transmitted disease clinics: testing, screening, and prevalence Sex Transm Dis. 2013;40:865-9
31. Schwebke JR, Rompalo A, Taylor S, et al. Re-evaluating the treatment of nongonococcal urethritis: emphasizing emerging pathogens-a randomized clinical trial Clin Infect Dis. 2011;52:163-70
32. Datta SD, Sternberg M, Johnson RE, et al. Gonorrhea and chlamydia in the United States among persons 14 to 39 years of age, 1999 to 2002 Ann Intern Med. 2007;147:89-96
33. Lazenby GB, Soper DE, Nolte FS. Correlation of leukorrhea and Trichomonas vaginalis infection J Clin Microbiol. 2013;51:2323-7
34. Martin DH, Zozaya M, Lillis RA, et al. Unique vaginal microbiota that includes an unknown Mycoplasma-like organism is associated with Trichomonas vaginalis infection J Infect Dis. 2013;207:1922-31
35. Nugent RP, Krohn MA, Hillier SL. Reliability of diagnosing bacterial vaginosis is improved by a standardized method of Gram stain interpretation J Clin Microbiol. 1991;29:297-301
36. Hillier SL, Krohn MA, Nugent RP, et al. Characteristics of three vaginal flora patterns assessed by Gram stain among pregnant women. Vaginal Infections and Prematurity Study Group Am J Obstet Gynecol. 1992;166:938-44
37. Brotman RM, Klebanoff MA, Nansel TR, et al. Bacterial vaginosis assessed by gram stain and diminished colonization resistance to incident gonococcal, chlamydial, and trichomonal genital infection J Infect Dis. 2010;202:1907-15
38. McGrory T, Meysick K, Lemchuk-Favel LT, et al. The interaction of Lactobacillus acidophilus and Trichomonas vaginalis in vitro J Parasitol. 1994;80:50-4
39. Rein MF, Muller MHolmes KK, Mardh PA, Sparling PF, Weisner PJ Sexually transmitted diseases. 1984 New York McGraw-Hill:525-35 Trichomonas vaginalis
40. Lossick JGHonigberg BM. Epidemiology of urogenital trichomoniasis Trichomonads parasitic in humans. 1989 New York Springer-Verlag:311-23
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Language: | English.
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Document Type: | ARTICLES AND COMMENTARIES.
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Journal Subset: | Clinical Medicine. Life & Biomedical Sciences.
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ISSN: | 1058-4838
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DOI Number: | https://dx.doi.org/10.1093/cid/c...- ouverture dans une nouvelle fenêtre
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