Epidermal growth factor receptor-targeted immunoliposomes for delivery of celecoxib to cancer cells.
Limasale, Yanuar Dwi Putra a; Tezcaner, Aysen a,b,c; Ozen, Can a,c; Keskin, Dilek a,b,c; Banerjee, Sreeparna a,d,*
[Miscellaneous Article]
International Journal of Pharmaceutics.
479(2):364-373, February 2015.
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* Design of an immunoliposomal delivery system for hydrophobic drug celecoxib.
* Celecoxib was encapsulated in EGFR antibody grafted immunoliposomes.
* Significant cellular association and internalization into EGFR expressing cancer cells.
* Significant reduction in proliferation of EGFR overexpressing cancer cells.
(C) 2015Elsevier, Inc.