Epidermal growth factor receptor-targeted immunoliposomes for delivery of celecoxib to cancer cells.
Limasale, Yanuar Dwi Putra a; Tezcaner, Aysen a,b,c; Ozen, Can a,c; Keskin, Dilek a,b,c; Banerjee, Sreeparna a,d,*
[Miscellaneous Article] International Journal of Pharmaceutics. 479(2):364-373, February 2015.

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* Design of an immunoliposomal delivery system for hydrophobic drug celecoxib.

* Celecoxib was encapsulated in EGFR antibody grafted immunoliposomes.

* Significant cellular association and internalization into EGFR expressing cancer cells.

* Significant reduction in proliferation of EGFR overexpressing cancer cells.

(C) 2015Elsevier, Inc.