Nomenclature for N-acetyltransferases.
Vatsis, Kostas P. 1; Weber, Wendell W. 1; Bell, Douglas A. 2; Dupret, Jean-Marie 3; Evans, David A. Price 4; Grant, Denis M. 5; Hein, David W. 6; Lin, Henry J. 7; Meyer, Urs A. 8; Relling, Mary V. 9; Sim, Edith 10; Suzuki, Tomokazu 11; Yamazoe, Yasushi 12
[Review]
Pharmacogenetics.
5(1):1-17, February 1995.
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A consolidated classification system is described for prokaryotic and eukaryotic N-acetyltransferases in accordance with the international rules for gene nomenclature. The root symbol (NAT) specifically identifies the genes that code for the N-acetyltransferases, and NAT* loci encoding proteins with similar function are distinguished by Arabic numerals. Allele characters, denoted by Arabic numbers or by a combination of Arabic numbers and uppercase Latin letters, are separated from gene loci by an asterisk, and the entire gene-allele symbols are italicized. Alleles at the different NAT* loci have been numbered chronologically irrespective of the species of origin. For designation of genotypes at a single NAT* locus, a slash serves to separate the alleles; in phenotype designations, which are not italicized, alleles are separated by a comma.
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