Information de reference pour ce titreAccession Number: | 00008571-199502000-00001.
|
Author: | Vatsis, Kostas P. 1; Weber, Wendell W. 1; Bell, Douglas A. 2; Dupret, Jean-Marie 3; Evans, David A. Price 4; Grant, Denis M. 5; Hein, David W. 6; Lin, Henry J. 7; Meyer, Urs A. 8; Relling, Mary V. 9; Sim, Edith 10; Suzuki, Tomokazu 11; Yamazoe, Yasushi 12
|
Institution: | (1)Department of Pharmacology, 1301 Medical Sciences Research Building 111, Medical School, The University of Michigan, 1150 West Medical Center Drive, Ann Arbor, Ml 48109-0632, USA (2)Laboratory of Biochemical Risk Analysis, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA (3)INSERM U120, Hopital Robert Debre, 75019 Paris, France (4)Department of Medicine, Riyadh Armed Forces Hospital, Riyadh 11159, Kingdom of Saudi Arabia (5)Division of Clinical Pharmacology and Toxicology, Research Institute, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada (6)Department of Pharmacology and Toxicology, School of Medicine, University of North Dakota, Grand Forks, ND 58202, USA (7)Division of Medical Genetics, Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA 90509, USA (8)Department of Pharmacology, Biozentrum of the University of Basel, 4056 Basel, Switzerland (9)Pharmaceutical Department, St. Jude Children's Research Hospital, Memphis, TN 38101, USA (10)Department of Pharmacology, University of Oxford, Oxford 0X1 3QT, UK (11)Department of Clinical Genetics, Medical Institute of Bioregulation, Kyushu University, Beppu 874, Japan (12)Department of Pharmacology, School of Medicine, Keio University, Tokyo 160, Japan
|
Title: | |
Source: | Pharmacogenetics. 5(1):1-17, February 1995.
|
Abstract: | A consolidated classification system is described for prokaryotic and eukaryotic N-acetyltransferases in accordance with the international rules for gene nomenclature. The root symbol (NAT) specifically identifies the genes that code for the N-acetyltransferases, and NAT* loci encoding proteins with similar function are distinguished by Arabic numerals. Allele characters, denoted by Arabic numbers or by a combination of Arabic numbers and uppercase Latin letters, are separated from gene loci by an asterisk, and the entire gene-allele symbols are italicized. Alleles at the different NAT* loci have been numbered chronologically irrespective of the species of origin. For designation of genotypes at a single NAT* locus, a slash serves to separate the alleles; in phenotype designations, which are not italicized, alleles are separated by a comma.
(C) Lippincott-Raven Publishers.
|
Author Keywords: | Acetylation polymorphisms; NAT nomenclature; N-acetyltransferases.
|
Language: | English.
|
Document Type: | Invited review: PDF Only.
|
Journal Subset: | Clinical Medicine. Life Sciences.
|
ISSN: | 0960-314X
|
NLM Journal Code: | brt, 9211735
|
Annotation(s) | |
|
|