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IMPORTANCE: To our knowledge, this is a report of the first implantation of a wireless intraocular pressure transducer (WIT) in a human eye.

OBJECTIVE: To report preliminary safety data on the WIT.

DESIGN, SETTING, AND PARTICIPANT: In an institutional setting, a patient with open-angle glaucoma consented to be the recipient of the WIT in one eye in an interventional study design.

INTERVENTIONS: The WIT was implanted into the ciliary sulcus following extracapsular cataract extraction and "in the bag" intraocular lens implantation. The patient was monitored postoperatively for 18 months.

MAIN OUTCOMES AND MEASURES: Any adverse events.

RESULTS: There were no complications noted during the WIT insertion or postoperatively. No persistent intraocular inflammation, pigment dispersion, or angle narrowing was noted.

CONCLUSIONS AND RELEVANCE: The WIT was well tolerated in the eye and no overt signs of toxicity or other adverse events were noted. This may allow the constant monitoring of intraocular pressure in the future.

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