Psychological outcomes of siblings of cancer survivors: a report from the Childhood Cancer Survivor Study.
Buchbinder, David 1,*; Casillas, Jacqueline 2; Krull, Kevin R. 3; Goodman, Pam 4; Leisenring, Wendy 4; Recklitis, Christopher 5; Alderfer, Melissa A. 6; Robison, Leslie L. 3; Armstrong, Gregory T. 3; Kunin-Batson, Alicia 7; Stuber, Margaret 2; Zeltzer, Lonnie K. 2
[Article]
Psycho-Oncology.
20(12):1259-1268, December 2011.
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Objective: To identify risk factors for adverse psychological outcomes among adult siblings of long-term survivors of childhood cancer.
Methods: Cross-sectional, self-report data from 3083 adult siblings (mean age 29 years, range 18-56 years) of 5 year survivors of childhood cancer were analyzed to assess psychological outcomes as measured by the Brief Symptom Inventory-18 (BSI-18). Sociodemographic and health data, reported by both the siblings and their matched cancer survivors, were explored as risk factors for adverse sibling psychological outcomes through multivariable logistic regression.
Results: Self-reported symptoms of psychological distress, as measured by the global severity index of the BSI-18, were reported by 3.8% of the sibling sample. Less than 1.5% of siblings reported elevated scores on two or more of the subscales of the BSI-18. Risk factors for sibling depression included having a survivor brother (OR 2.22, 95% CI 1.42-3.55), and having a survivor with impaired general health (OR 2.15, 95% CI 1.18-3.78). Siblings who were younger than the survivor reported increased global psychological distress (OR 1.81, 95% CI 1.05-3.12), as did siblings of survivors reporting global psychological distress (OR 2.32, 95% CI 1.08-4.59). Siblings of sarcoma survivors reported more somatization than did siblings of leukemia survivors (OR 2.07, 95% CI 1.05-3.98).
Conclusions: These findings suggest that siblings of long-term childhood cancer survivors are psychologically healthy in general. There are, however, small subgroups of siblings at risk for long-term psychological impairment who may benefit from preventive risk-reduction strategies during childhood while their sibling with cancer is undergoing treatment. Copyright (C) 2010 John Wiley & Sons, Ltd.
Copyright (C) 2011 John Wiley & Sons, Inc.