Information de reference pour ce titreAccession Number: | 01445403-201202000-00008.
|
Author: | Baker, Arthur M. 1; Haeri, Sina 2; Camargo, Carlos A. Jr. 3,4; Stuebe, Alison M. 5,6; Boggess, Kim A. 5
|
Institution: | (1) Memorial Health University Medical Center, Mercer School of Medicine, Savannah Campus, Savannah, GA, (2) Division of Maternal-Fetal Medicine, Department of Obstetrics, and Gynecology, Baylor College of Medicine, Houston, TX, (3) Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, (4) Center for D-receptor Activation Research, Massachusetts General Hospital, Boston, MA, (5) Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC, (6) Department of Maternal and Child Health, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC,
|
Title: | |
Source: | Diabetes/Metabolism: Research & Reviews. 28(2):164-168, February 2012.
|
Abstract: | Background: Vitamin D deficiency may contribute to impaired glucose metabolism. There are sparse data regarding vitamin D and the development of gestational diabetes (GDM). The objective of this study was to assess if first-trimester vitamin D deficiency is more prevalent in women later diagnosed with GDM compared with women with uncomplicated pregnancies.
Methods: We conducted a nested case-control study of pregnant women who had previously given blood for routine genetic multiple marker screening and subsequently delivered at a tertiary hospital between November 2004 and July 2009. From an overall cohort of 4225 women, 60 cases of GDM were matched by race/ethnicity with 120 women delivering at term (>=37 weeks) with uncomplicated pregnancies. Banked maternal serum was used to measure maternal 25-hydroxyvitamin D [25(OH)D].
Results: The prevalence of first-trimester maternal vitamin D deficiency (defined as 25(OH)D < 50 nmol/L) was comparable among women with GDM compared with controls (5/60 vs 8/120, p = 0.90). The median 25(OH)D level for all subjects was 89 nmol/L (interquartile range, 73-106 nmol/L). Seventy three percent (117/160) of the cohort had 25(OH)D levels >=75 nmol/L.
Conclusions: In a cohort of pregnant women with mostly sufficient levels of serum 25(OH)D, vitamin D deficiency was not associated with GDM. Further studies are warranted with larger cohorts, especially in populations with lower levels of vitamin D.
Copyright (C) 2012 John Wiley & Sons, Inc.
|
Author Keywords: | gestational diabetes; pregnancy; vitamin D; 25-hydroxyvitamin D.
|
References: | 1. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care, 2008; 31(Suppl 1): S55-S60.
2. Kim C, Newton KM, Kopp RH Gestational diabetes and the incidence of type 2 diabetes: a systematic review. Diabetes Care, 2002; 25: 1862-1868.
3. King H, Aubert RE, Herman WH Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care, 1998; 21: 1414-1431.
4. Dabelea D, Snell-Bergeou JK, Hartsfield CL, Bischoff KJ, Hamman RF, McDuffie RS Increasing prevalence of gestational diabetes mellitus (GDM) over time and by birth cohort: Kaiser Permanente of Colorado GDM Screening Program. Diabetes Care, 2005; 28: 579-584.
5. Langer O, Yogev Y, Most O, Xenakis EM Gestational diabetes: the consequences of not treating. Am J Obstet Gynecol, 2005; 192(4): 989-997.
6. Silverman BL, Metzger BE, Cho NH, Loeb CA Impaired glucose tolerance in adolescent offspring of diabetic mother. Relationships to fetal hyperinsulinism. Diabetes Care, 1995; 18(5): 611-617.
7. Petitt DJ, Bennett PH, Knowler WC, Baird HR, Aleck KA Gestational diabetes mellitus and impaired glucose tolerance during pregnancy. Long-term effects on obesity and glucose tolerance in the offspring. Diabetes, 1985; 34(Suppl 2): 119-122.
8. Forouhi NG, Luan J, Cooper A, Boucher BJ, Wareham NJ Baseline serum 25-hydroxy vitamin D is predictive of future glycemic status and insulin resistance: the Medical Research Council Ely Prospective Study 1990-2000. Diabetes, 2008; 57(10): 2619-2625.
9. Kositsawat J, Freeman VL, Gerber BS, Geraci S Association of A1C levels with vitamin D status in U.S. adults: data from the National Health and Nutrition Examination Survey. Diabetes Care, 2010; 33(6): 1236-1238.
10. Chiu KC, Chu A, Go VL, Saad MF Hypovitaminosis D is associated with insulin resistance and beta cell dysfunction. Am J Clin Nutr, 2004; 79(5): 820-825.
11. Maghbooli Z, Hossein-Nezhad A, Karimi F, Shafaei AR, Larijani B Correlation between vitamin D3 deficiency and insulin resistance in pregnancy. Diabetes Metab Res Rev, 2008; 24(1): 27-32.
12. Clifton-Bligh RJ, McElduff P, McElduff A Maternal vitamin D deficiency, ethnicity and gestational diabetes. Diabet Med, 2008; 25(6): 678-684.
13. Zhang C, Qui C, Hu FB et al. Maternal plasma 25-hydroxyvitamin D concentrations and the risk for gestational diabetes mellitus. PLoS One, 2008; 3(11): e3753.
14. National Diabetes Data Group. Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes, 1979; 28(12): 1039-1057.
15. Roth HJ, Schmidt-Gayk H, Weber H, Niederau C Accuracy and clinical implications of seven 25-hydroxyvitamin D methods compared with liquid chromatography-tandem mass spectrometry as a reference. Ann Clin Biochem, 2008; 45: 153-159.
16. Singh RJ, Taylor RL, Reddy GS, Grebe SKG C-3 epimers can account for a significant proportion of total circulating 25-hydroxyvitamin D in infants, complicating accurate measurement and interpretation of vitamin D status. J Clin Endocrinol Metab, 2006; 91: 3055-3061.
17. Holick MF, Vitamin D deficiency. N Engl J Med, 2007; 357(3): 266-281.
18. Canadian Paediatric Society. Vitamin D supplementation: recommendations for Canadian mothers and infants. Paediatr Child Health, 2007; 12(7): 583-598.
19. Ginde AA, Sullivan AF, Mansbach JM, Camargo CA Jr Vitamin D insufficiency in pregnant and nonpregnant women of childbearing age in the United States. Am J Obstet Gynecol, 2010; 202(5): 436.e1-436.e8.
20. Kim J, Lee JS, Shin A et al. Sociodemographic and lifestyle factors are associated with the use of dietary supplements in a Korean population. J Epidemiol, 2010; 20(3): 197-203.
21. Adams JS, Hewison M Update in vitamin D. J Clin Endocrinol Metab, 2010; 95(2): 471-478.
22. Souberbielle JC, Body JJ, Lappe JM et al. Vitamin D and musculoskeletal health, cardiovascular disease, autoimmunity and cancer: recommendations for clinical practice. Autoimmun Rev, 2010; 9(11): 709-715.
23. Boggess K. A., Espinola J. A., Moss K., Beck J., Offenbacher S., Camargo C. A. Vitamin D status and periodontal disease among pregnant women. J Periodontol, 2010; Sept 1 (epub ahead of print) doi: 10.1902/jop.2010.100384.
24. Baker AM, Haeri S, Camargo CA Jr, Espinola JA, Stuebe AM A nested case-control study of midgestation vitamin D deficiency and risk of severe preeclampsia. J Clin Endocrinol Metab, 2010; 95(11): 5105-5109.
25. Bodnar LM, Simhan HN Vitamin D may be a link to black-white disparities in adverse birth outcomes. Obstet Gynecol Surv, 2010; 65(4): 273-284.
|
Language: | English.
|
Document Type: | RESEARCH ARTICLES.
|
Journal Subset: | Clinical Medicine.
|
ISSN: | 1520-7552
|
DOI Number: | https://dx.doi.org/10.1002/dmrr....- ouverture dans une nouvelle fenêtre
|
Annotation(s) | |
|
|