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Summary: GWAF, Genome-Wide Association analyses with Family, is an R package designed for GWAF. It implements association tests between a batch of genotyped or imputed single nucleotide polymorphisms (SNPs) and a binary or continuous trait with user specified genetic model, and generates informative results from the analyses. In addition, GWAF provides functions to visualize results. We evaluated GWAF using a simulated continuous trait and a binary trait dichotomized from the simulated continuous trait with real genotype data from the Framingham Heart Study's SNP Health Association Resource project.

Availability: http://cran.r-project.org/web/packages/GWAF/

Contact: [email protected]

Supplementary information: Supplementary data are available at Bioinformatics online.

(C) Copyright Oxford University Press 2010.