Establishment and comparison of three novel methods for the determination of the photodynamic therapy agent 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a (HPPH) in human serum.
Chen, Lin; Xiao, Qingqing; Zhang, Xian; Yang, Jin
[Article] Journal of Pharmaceutical and Biomedical Analysis. 121 Supplement C:13-21, March 2016.

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* The first clinical pharmacokinetic study of HPPH in Chinese was reported.

* Three novel methods were proposed and validated for the determination of HPPH.

* Comparison of fluorescence and MS platform for HPPH quantification was achieved.

* Data consistency was found among proposed three methods.

* Microplate reader method was recommended because of very rapid determination.

(C) 2016Elsevier, Inc.