Management of haemophilia B inhibitor patients with anaphylactic reactions to FIX concentrates.
SHIBATA, M. *; SHIMA, M. *; MISU, H. +; OKIMOTO, Y. ++; GIDDINGS, J. C. [S]; YOSHIOKA, A. *
[Article] Haemophilia. 9(3):269-271, May 2003.

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Summary: Allergic reactions to concentrates containing factor IX (FIX) are serious complications in the treatment of haemophilia B patients with inhibitor. We have established a therapeutic protocol for such cases using an initial skin test followed by step-wise infusions of FIX concentrates under hydrocortisone cover. We have successfully treated three patients whose treatment with FIX had been suspended.

(C) 2003 Blackwell Science Ltd.