Effect of Menses on Clearance of Y-Chromosome in Vaginal Fluid: Implications for a Biomarker of Recent Sexual Activity.
Brotman, Rebecca M. PHD, MPH *; Melendez, Johan H. MS +; Smith, Tukisa D. MS +; Galai, Noya PHD ++[S]; Zenilman, Jonathan M. MD +
Sexually Transmitted Diseases.
37(1):1-4, January 2010.
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Self-reported sexual behaviors are subject to bias. We previously developed a polymerase chain reaction for the detection of Y-chromosome sequences in vaginal fluid as a potential biomarker of recent sexual activity. In this study, we found menses results in lower Y-chromosome concentrations but with similar decay patterns as non-menstrual samples.
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