Pancreatic islets from cyclin-dependent kinase 4/R24C (Cdk4) knockin mice have significantly increased beta cell mass and are physiologically functional, indicating that Cdk4 is a potential target for pancreatic beta cell mass regeneration in Type 1 diabetes.
Marzo, N. 1; Mora, C. 1; Fabregat, M. E. 1; Martin, J. 2; Usac, E. F. 1; Franco, C. 1; Barbacid, M. 2; Gomis, R. 1
47(4):686-694, April 2004.
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