Information de reference pour ce titreAccession Number: | 00003439-199803000-00028.
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Author: | Vigouroux, Corinne; Fajas, Lluis; Khallouf, Eliane; Meier, Muriel; Gyapay, Gabor; Lascols, Olivier; Auwerx, Johan; Weissenbach, Jean; Capeau, Jacqueline; Magre, Jocelyne
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Institution: | From INSERM U.402 (C. Vigouroux, M. Meier, O. Lascols, J. Capeau, J. Magre), Saint-Antoine School of Medicine, Paris; INSERM U.325 (L. Fajas, J. Auwerx), Pasteur Institute, Lille; CNRS URA 1922 (G. Gyapay, J. Weissenbach), Genethon, Evry, France; and the Department of Pediatric Endocrinology (E. Khallouf), Hotel-Dieu Hospital, Beirut, Lebanon. Address correspondence and reprint requests to Dr. J. Magre, INSERM U.402, Faculte de Medecine Saint-Antoine, 27 Rue Chaligny, 75571 Paris Cedex 12, France: E-mail: [email protected]. Received for publication 30 July 1997 and accepted in revised form 24 November 1997. GDB accession numbers: Polymorphism: 6382894, Amplimer: 6380701, Cytolocation: 6382897. Additional information can be found in an on-line appendix at www.diabetes.org/diabetes/appendix.htm.
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Title: | Human Peroxisome Proliferator-Activated Receptor-gamma 2: Genetic Mapping, Identification of a Variant in the Coding Sequence, and Exclusion as the Gene Responsible for Lipoatrophic Diabetes.[Report]
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Source: | Diabetes. 47(3):490-492, March 1998.
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References: | 1. Brun RP, Kim JB, Hu E, Altiok S, Spiegelman BM: Adipocyte differentiation: a transcriptional regulatory cascade. Curr Opin Cell Biol 8:826-832, 1996.
2. Fajas L, Auboeuf D, Raspe E, Schoonjans K, Lefebvre AM, Saladin R, Najib J, Laville M, Fruchart JC, Deeb S, Puig-Vidal A, Flier J, Briggs MR, Vidal H, Staels B, Auwerx J: The human PPAR gamma gene: organization, promoter analysis, and expression. J Biol Chem 272:18779-18789, 1997
3. Dib C, Faure S, Fizames C, Samson D, Drouot N, Vignal A, Millasseau P, Marc S, Hazan J, Seboun E, Lathrop M, Gyapay G, Morissette J, Weissenbach J: A comprehensive genetic map of the human genome based on 5,264 microsatellites. Nature 380:152-154, 1996
4. Gyapay G, Schmitt K, Fizames C, Jones H, Vega-Czarny N, Spillett D, Muselet D, Prud'Homme JF, Dib C, Auffray C, Morissette J, Weissenbach J, Goodfellow PN: A radiation hybrid map of the human genome. Hum Mol Genet 5:339-346, 1996
5. Vigouroux C, Khallouf E, Bourut C, Robert JJ, De Kerdanet M, Tubiana-Rufi N, Faure S, Weissenbach J, Capeau J, Magre J: Genetic exclusion of fourteen candidate genes in lipoatrophic diabetes using linkage analysis in ten consanguineous families. J Clin Endocrinol Metab 82:3438-3444, 1997
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11. Desbois C, Magre J, Blanquet V, Capeua C, Goossens M, Besmond C: Detection of sequence variations in the human insulin-receptor gene by parallel denaturing gradient gel electrophoresis. Hum Mutat 2:395-403, 1993
12. Okazawa H, Mori H, Tamori Y, Araki S, Niki T, Masugi J, Kawanishi M, Kubota T, Shinoda H, Kasuga M: No coding mutations are detected in the peroxisome proliferator-activated receptor-gamma gene in Japanese patients with lipoatrophic diabetes. Diabetes 46:1904-1906, 1997
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Language: | English.
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Document Type: | Brief Genetics Reports.
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Journal Subset: | Clinical Medicine.
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ISSN: | 0012-1797
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NLM Journal Code: | e8x, 0372763
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