Optical Coherence Tomography and Ultrasound Biomicroscopy Imaging of Opaque Corneas.
Zhou, Shi-you MD, PhD; Wang, Chun-xiao MD; Cai, Xiao-yu MD; Huang, David MD, PhD; Liu, Yi-zhi MD, PhD
32(4):e25-e30, April 2013.
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Purpose: The purpose was to determine the interchangeability of ultrasound biomicroscopy (UBM) and anterior segment optical coherence tomography (AS-OCT) for corneal opacity depth measurement.
Methods: Twenty-six eyes of 26 consecutive patients with corneal opacities were examined by both AS-OCT and UBM. The corneal thickness and the corneal opacity depth were measured and compared. The interchangeability was determined by Bland-Altman plotting.
Results: The difference in the full corneal thickness and in the corneal opacity depth between OCT and UBM was 5 /- 7 [mu]m and -1 /- 8 [mu]m, respectively. There were strong correlations and no significant differences between the paired parameters (all r > 0.99, P < 0.01). The limits of agreement were 5 /- 14 [mu]m for the corneal thickness and -1 /- 14.8 [mu]m for the corneal opacity depth.
Conclusions: AS-OCT and UBM may be used interchangeably for measuring both full corneal thickness and corneal opacity depth in patients with corneal opacity.
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