Information de reference pour ce titreAccession Number: | 00000620-200711050-00002.
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Author: | SJOSTEDT, ANDERS
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Institution: | Department of Clinical Bacteriology, Clinical Microbiology, Umea University, SE-901 85 Umea, Sweden
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Title: | |
Source: | Annals of the New York Academy of Sciences. 1105(1):1-29, June 2007.
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Abstract: | Francisella tularensis has been recognized as a human pathogen for almost 100 years and is the etiological agent of the zoonotic disease tularemia. Soon after its discovery, it became recognized as an important pathogen in several parts of the world, for example, in the United States and Soviet Union. The number of tularemia cases in the two countries peaked in the 1940s and has thereafter steadily declined. Despite this decline, there was still much interest in the pathogen in the 1950s and 1960s since it is highly infectious and transmissible by aerosol, rendering it a potent biothreat agent. In fact, it was one of the agents that was given the highest priority in the offensive programs of the United States and Soviet Union. After termination of the offensive programs in the 1960s, the interest in F. tularensis diminished significantly and little research was carried out for several decades. Outbreaks of tularemia during the last decade in Europe, for example, in Kosovo, Spain, and Scandinavia, led to a renewed public interest in the disease. This, together with a massive increase in the research funding, in particular in the United States since 2001, has resulted in a significant increase in the number of active Francisella researchers. This article summarizes, predominantly with a historical perspective, the epidemiology and clinical manifestations of tularemia and the physiology of F. tularensis.
Copyright 2007 by the New York Academy of Sciences. All rights reserved.
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Author Keywords: | Francisella; tularemia; epidemiology; pathogen physiology; clinical manifestations.
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References: | 1. MCCOY, G.W. & C.W. CHAPIN. 1912. Further observations on a plague-like disease of rodents with a preliminary note on the causative agent, Bacterium tularense. J. Infect. Dis. 10: 61-72.
2. PEARSE, R.A. 1911. Insect bites. Northwest Med. 3: 81-82.
3. MORNER, T. 1992. The ecology of tularaemia. Rev. Sci. Tech. 11: 1123-1130.
4. OHARA, S. 1954. Studies on yato-byo (Ohara's disease, tularemia in Japan). I. Jpn. J. Exp. Med. 24: 69-79.
5. SCHEEL, O. et al. 1992. [Tularemia in Norway. A clinical and epidemiological review]. Tidsskr. Nor. Laegeforen. 112: 635-670.
6. WHERRY, W.B. & B.H. LAMB. 1914. Infection of man with Bacterium tularense. J. Infect. Dis. 15: 331-340.
7. DENNIS, D.T. et al. 2001. Tularemia as a biological weapon: medical and public health management. J. Am. Med. Assoc. 285: 2763-2773.
8. ALIBEK, K. 1999. Biohazard, 29-38. N.R. & House. New York.
9. GOLD, H. 2004. Unit 731 Testimony. Tuttle Publishing. North Clarendon, VT.
10. ANONYMOUS. 1970. Health Aspects of Chemical and Biological Weapons. World Health Organization. Geneva, Switzerland.
11. KAUFMANN, A.F., M.I. MELTZER & G.P. SCHMID. 1997. The economic impact of a bioterrorist attack: are prevention and postattack intervention programs justifiable? Emerg. Infect. Dis. 3: 83-94.
12. FRANCIS, E. 1919. Deer-fly fever - a disease of hitherto unknown etiology. Public Health Rep. 34: 2061-2062.
13. RITTER, D.B. & R.K. GERLOFF. 1966. Deoxyribonucleic acid hybridization among some species of the genus Pasteurella. J. Bacteriol. 92: 1838-1839.
14. FORSMAN, M., G. SANDSTROM & A. SJOSTEDT. 1994. Analysis of 16S ribosomal DNA sequences of Francisella strains and utilization for determination of the phylogeny of the genus and for identification of strains by PCR. Int. J. Syst. Bacteriol. 44: 38-46.
15. SJOSTEDT, A.B. 2005. Francisella. In The Proteobacteria, Part B, Bergey's Manual of Systematic Bacteriology, Vol. 2, 2nd ed. D.J. Brenner, J.T. Staley & G.M. Garrity, Eds.: 200-210. Springer. New York, NY.
16. FRYER, J.L. et al. 1992. Piscirickettsia salmonis gen. nov., sp. nov., the causative agent of an epizootic disease in salmonid fishes. Int. J. Syst. Bacteriol. 42: 120-126.
17. NYLUND, A. et al. 2006. Francisella sp. (Family Francisellaceae) causing mortality in Norwegian cod (Gadus morhua) farming. Arch. Microbiol. 185: 383-392.
18. OTTEM, K.F. et al. 2006. Characterization of Francisella sp., GM2212, the first Francisella isolate from marine fish, Atlantic cod (Gadus morhua). Arch. Microbiol.
19. HOOD, A.M. 1977. Virulence factors of Francisella tularensis. J. Hyg. (Lond.) 79: 47-60.
20. OLSUFIEV, N.G., O.S. EMELYANOVA & T.N. DUNAEVA. 1959. Comparative studies of strains of B. tularense in the Old and New World and their taxonomy. J. Hyg. Epidemiol. Microbiol. Immunol. (Prague) 3: 138-149.
21. OLSUFIEV, N.G. 1970. Taxonomy and characteristic of the genus Francisella Dorofeev, 1947. J. Hyg. Epidemiol. Microbiol. Immunol. 14: 67-74.
22. OLSUFIEV, N.G. & I.S. MESHCHERYAKOVA. 1982. Infraspecific taxonomy of tularemia agent Francisella tularensis McCoy et Chapin. J. Hyg. Epidemiol. Microbiol. Immunol. 26: 291-299.
23. JELLISON, W. 1974. Tularemia in North America. 1930-1974. University of Montana. Missoula, Montana.
24. LARSON, C.L., W. WICHT & W.L. JELLISON. 1955. A new organism resembling P. tularensis isolated from water. Public Health Rep. 70: 253-258.
25. HOLLIS, D.G. et al. 1989. Francisella philomiragia new combination formerly Yersinia-Philomiragia and Francisella tularensis biogroup novicida formerly Francisella novicida associated with human disease. J. Clin. Microbiol. 27: 1601-1608.
26. ANTHONY, L.S. et al. 1991. Transformation and allelic replacement in Francisella spp. J. Gen. Microbiol. 137: 2697-2703.
27. CLARRIDGE, J.E.R. et al. 1996. Characterization of two unusual clinically significant Francisella strains. J. Clin. Microbiol. 34: 1995-2000.
28. STAPLES, J.E. et al. 2006. Epidemiologic and molecular analysis of human tularemia, United States, 1964-2004. Emerg. Infect. Dis. 12: 1113-1118.
29. SASLAW, S. et al. 1961. Tularemia vaccine study. II. Respiratory challenge. Arch. Intern. Med. 107: 702-714.
30. SASLAW, S. et al. 1961. Tularemia vaccine study. I. Intracutaneous challenge. Arch. Intern. Med. 107: 689-701.
31. HOPLA, C.E. 1974. The ecology of tularemia. Adv. Vet. Sci. Comp. Med. 18: 25-53.
32. JENSEN, W.I., C.R. OWEN & W.L. JELLISON. 1969. Yersinia philomiragia sp. n., a new member of the Pasteurella group of bacteria, naturally pathogenic for the muskrat (Ondatra zibethica). J. Bacteriol. 100: 1237-1241.
33. URSING, J., A.G. STEIGERWALT & D.J. BRENNER. 1980. Lack of genetic relatedness between Yersinia philomiragia (the "Philomiragia" bacterium) and Yersinia species. Curr. Microbiol. 4: 231-233.
34. BERCOVIER, H. & H.H. MOLLARET. 1984. Yersinia. In Bergey's Manual of Systematic Bacteriology, Vol. 1, 1st ed. Krieg, N.R. and Holt, J.G., Ed.: 503-506. The Williams & Wilkins Co. Baltimore.
35. WENGER, J.D. et al. 1989. Infection caused by Francisella philomiragia (formerly Yersinia philomiragia). A newly recognized human pathogen. Ann. Intern. Med. 110: 888-92.
36. BEIER, C.L. et al. 2002. The genus Caedibacter comprises endosymbionts of Paramecium spp. related to the Rickettsiales (Alphaproteobacteria) and to Francisella tularensis (Gammaproteobacteria). Appl. Environ. Microbiol. 68: 6043-6050.
37. BARNS, S.M. et al. 2005. Detection of diverse new Francisella-like bacteria in environmental samples. Appl. Environ. Microbiol. 71: 5494-5500.
38. FRANCIS, E. 1927. Microscopic changes of tularemia in the tick Dermacentor andersoni and the bedbug Cimex lectularius. Public Health Rep. 42: 2763-2772.
39. TARNVIK, A. 1989. Nature of protective immunity to Francisella tularensis. Rev. Infect. Dis. 11: 440-451.
40. KOSTIALA, A.A.I., P. LOGIE & D.D. MCGREGOR. 1975. The immune response to Francisella tularensis in rats. Immunology. 2: 855-869.
41. CONLAN, J.W. & R.J. NORTH. 1992. Early pathogenesis of infection in the liver with the facultative intracellular bacteria Listeria monocytogenes, Francisella tularensis, and Salmonella typhimurium involves lysis of infected hepatocytes by leukocytes. Infect. Immun. 60: 5164-5171.
42. BOSIO, C.M. & S.W. DOW. 2005. Francisella tularensis induces aberrant activation of pulmonary dendritic cells. J. Immunol. 175: 6792-8801.
43. HALL, J.D. et al. 2007. Francisella tularensis replicates within alveolar type II epithelial cells in vitro and in vivo following inhalation. Infect. Immun. 75: 1034-1039.
44. WHITE, J.D. et al. 1964. Pathogenesis of experimental respiratory tularemia in monkeys. J. Infect. Dis. 114: 277-283.
45. GOLOVLIOV, I. et al. 2003. An attenuated strain of the facultative intracellular bacterium Francisella tularensis can escape the phagosome of monocytic cells. Infect. Immun. 71: 5940-5950.
46. CLEMENS, D.L., B.Y. LEE & M.A. HORWITZ. 2004. Virulent and avirulent strains of Francisella tularensis prevent acidification and maturation of their phagosomes and escape into the cytoplasm in human macrophages. Infect. Immun. 72: 3204-3217.
47. SANTIC, M., M. MOLMERET & Y. ABU KWAIK. 2005. Modulation of biogenesis of the Francisella tularensis subsp. novicida-containing phagosome in quiescent human macrophages and its maturation into a phagolysosome upon activation by IFN-gamma. Cell Microbiol. 7: 957-967.
48. CHECROUN, C. et al. 2006. Autophagy-mediated reentry of Francisella tularensis into the endocytic compartment after cytoplasmic replication. Proc. Natl. Acad. Sci. USA 103: 14578-83.
49. LINDGREN, H. et al. 2004. Factors affecting the escape of Francisella tularensis from the phagolysosome. J. Med. Microbiol. 53: 953-958.
50. LAI, X.H., I. GOLOVLIOV & A. SJOSTEDT. 2001. Francisella tularensis induces cytopathogenicity and apoptosis in murine macrophages via a mechanism that requires intracellular bacterial multiplication. Infect. Immun. 69: 4691-4694.
51. LAI, X.H. & A. SJOSTEDT. 2003. Delineation of the molecular mechanisms of Francisella tularensis-induced apoptosis in murine macrophages. Infect. Immun. 71: 4642-4646.
52. LAI, X.H., I. GOLOVLIOV & A. SJOSTEDT. 2004. Expression of IglC is necessary for intracellular growth and induction of apoptosis in murine macrophages by Francisella tularensis. Microb. Pathog. 37: 225-230.
53. MACK, K. et al. 1994. A new cell assay to determine the virulence of Francisella tularensis. Lett. Appl. Microbiol. 19: 158-160.
54. HRSTKA, R., J. STULIK & B. VOJTESEK. 2005. The role of MAPK signal pathways during Francisella tularensis LVS infection-induced apoptosis in murine macrophages. Microbes Infect. 7: 619-625.
55. TELEPNEV, M. et al. 2003. Francisella tularensis inhibits Toll-like receptor-mediated activation of intracellular signalling and secretion of TNF-alpha and IL-1 from murine macrophages. Cell Microbiol. 5: 41-51.
56. FRANCIS, E. 1921. The occurrence of tularaemia in nature as a disease of man. Public Health Rep. 36: 1731-1753.
57. JELLISON, W.L. 1950. Tularemia; geographical distribution of deerfly fever and the biting fly, Chrysops discalis Williston. Public Health Rep. 65: 1321-1329.
58. OLSUFIEV, N.G. 1966. Tularemia. In Human Diseases with Natural Foci, Vol. 2. Y. Pavlovsky, Ed.: 219-281. Foreign Languages Publishing House. Moscow.
59. WHIPP, M.J. et al. 2003. Characterization of a novicida-like subspecies of Francisella tularensis isolated in Australia. J. Med. Microbiol. 52: 839-842.
60. OLSUFIEV, N.G. 1977. [Results and perspectives of the study of natural foci of tularemia in USSR]. Med Parazitol. (Mosk.) 46: 273-282.
61. TARNVIK, A., H.S. PRIEBE & R. GRUNOW. 2004. Tularaemia in Europe: an epidemiological overview. Scand. J. Infect. Dis. 36: 350-355.
62. ANDA, P. et al. 2001. Waterborne outbreak of tularemia associated with crayfish fishing. Emerg. Infect. Dis. 7: 575-582.
63. PEREZ-CASTRILLON, J.L. et al. 2001. Tularemia epidemic in northwestern Spain: clinical description and therapeutic response. Clin. Infect. Dis. 33: 573-576.
64. ELIASSON, H. et al. 2002. The 2000 tularemia outbreak: a case-control study of risk factors in disease-endemic and emergent areas, Sweden. Emerg. Infect. Dis. 8: 956-960.
65. REINTJES, R. et al. 2002. Tularemia outbreak investigation in Kosovo: case control and environmental studies. Emerg. Infect. Dis. 8: 69-73.
66. HAYES, E. et al. 2002. Tularemia - United States, 1990-2000. MMWR Morb. Mortal. Wkly. Rep. 51: 181-184.
67. TEUTSCH, S.M. et al. 1979. Pneumonic tularemia on Martha's Vineyard. N. Engl. J. Med. 301: 826-828.
68. FELDMAN, K.A. et al. 2003. Tularemia on Martha's vineyard: seroprevalence and occupational risk. Emerg. Infect. Dis. 9: 350-354.
69. EL'BERT, B. I., I.S. TINKER & T.I. PUCHKEVA. 1947. The cutaneous method of the specific prophylaxis of tularemia. Rostov. 6: 7-20.
70. OLSUFIEV, N.G. & D.A. GOLOV. 1936. Horse flies as transmitters and conservators of tularemia. Animaux Pathogen. Sect. Parasitol. 2: 187-226.
71. OLSUFIEV, N.G. 1940. Results of transmission of tularemia in the USSR. Works of the All-Union Conference Microbiologist, Epidemiologist & Infectionist.
72. OLSUFIEV, N.G. & T.N. DUNAYEVA. 1970. Natural focality, epidemiology and prophylaxis of tularemia. Medicina. 9: 11-18.
73. EFIMOV, V.M., Y. GALAKTIONOV & T.A. GALAKTIONOVA. 2003. Reconstruction and prognosis of water vole population dynamics on the basis of tularemia morbidity among Novosibirsk oblast residents. Dokl. Biol. Sci. 388: 59-61.
74. FRANCIS, E. 1942. Tularemia. In Tice's Practice of Medicine. Hagerstown, MD, W.F. Prior Co., Inc., Vol. 2, 603-678.
75. SHOEMAKER, D. et al. 1997. Humoral immune response of cottontail rabbits naturally infected with Francisella tularensis in southern Illinois. J. Wildl. Dis. 33: 733-737.
76. WASHBURN, A.M. & J.H. TOCKY. 1949. The changing picture of tularemia transmission in Arkansas. South. Med. J. 42: 60-62.
77. TAYLOR, J.P. et al. 1991. Epidemiologic characteristics of human tularemia in the southwest-central states, 1981-1987. Am. J. Epidemiol. 133: 1032-1038.
78. JELLISON, W.L. & G.M. KOHLS. 1955. Tularemia in sheep and in sheep industry workers in western United States. Public Health Monogr. 28: 1-19.
79. PARKER, R.R. et al. 1951. Contamination of natural waters and mud with Pasteurella tularensis and tularemia in beavers and muskrats in the northwestern United States. Bull. Natl. Inst. Health. 193: 1-161.
80. WOOD, W.J. 1951. Tularemia; a study based on the incidence of positive agglutination tests against P. tularensis in the Indian population of Manitoba and North-Western Ontario. Manit. Med. Rev. 31: 641-644.
81. BELL, J.F. & S.J. STEWART. 1983. Quantum differences in oral susceptibility of voles, Microtus pennsylvanicus, to virulent Francisella tularensis type B, in drinking water: implications to epidemiology. Ecol. Dis. 2: 151-155.
82. HENSON, J.B., J.R. GORHAM & D.T. SHEN. 1978. An outbreak of tularemia in mink. Cornell Vet. 68: 78-83.
83. PETERSEN, J.M. et al. 2004. Laboratory analysis of tularemia in wild-trapped, commercially traded prairie dogs, Texas, 2002. Emerg. Infect. Dis. 10: 419-425.
84. JOHANSSON, A. et al. 2004. Worldwide genetic relationships among Francisella tularensis isolates determined by multiple-locus variable-number tandem repeat analysis. J. Bacteriol. 186: 5808-5818.
85. FRANCIS, E. 1937. Sources of infection and seasonal incidence of tularaemia in man. Public Health Rep. 52: 103-113.
86. THJOTTA, T. 1930. Tularemia og dens forekomst i Norge. Nord. Med. T. 2: 177-180.
87. JUSATZ, H.J. 1952. Tularemia in Europe, 1926-1951. In Welt-Suchen Atlas, Vol. 1. E. Rodenwaldt, Ed.: 7-16. Falk-Verlag. Hamburg.
88. MORNER, T. et al. 1988. Infections with Francisella tularensis biovar palaearctica in hares (Lepus timidus, Lepus europaeus) from Sweden. J. Wildl. Dis. 24: 422-433.
89. HORNFELDT, B., O. LOFGREN & B.G. CARLSSON. 1986. Cycles in voles and small game in relation to variations in plant production indices in Northern Sweden. Oecologia (Berl.). 68: 496-502.
90. CERNY, Z. 2001. Changes of the epidemiology and the clinical picture of tularemia in Southern Moravia (the Czech Republic) during the period 1936-1999. Eur. J. Epidemiol. 17: 637-642.
91. DAHLSTRAND, S., O. RINGERTZ & B. ZETTERBERG. 1971. Airborne tularemia in Sweden. Scand. J. Infect. Dis. 3: 7-16.
92. OLIN, G. 1942. Occurrence and mode of transmission of tularemia in Sweden. Acta Microbiol. Scand. 19: 220-247.
93. MORNER, T., G. SANDSTROM & R. MATTSSON. 1988. Comparison of serum and lung extracts for surveys of wild animals for antibodies to Francisella tularensis biovar palaearctica. J. Wildl. Dis. 24: 10-14.
94. BERDAL, B.P. et al. 1996. Field investigations of tularemia in Norway. FEMS Immunol. Med. Microbiol. 13: 191-195.
95. LUOTONEN, J. et al. 1986. Tularemia in otolaryngologic practice. An analysis of 127 cases. Arch. Otolaryngol. Head Neck Surg. 112: 77-80.
96. TARNVIK, A., G. SANDSTROM & A. SJOSTEDT. 1997. Infrequent manifestations of tularaemia in Sweden. Scand. J. Infect. Dis. 29: 443-446.
97. OHARA, Y., T. SATO & M. HOMMA. 1998. Arthropod-borne tularemia in Japan: clinical analysis of 1,374 cases observed between 1924 and 1996. J. Med. Entomol. 35: 471-473.
98. GEISSLER, E. 2005. Alibek, tularaemia, and the battle of Stalingrad. CBW Convention Bull. September/December 2005. 10-15.
99. ROGOZIN, I.I. 1970. [Tularemia prevention during the Second World War]. Z. Mikrobiol. Epidemiol. Immunobiol. 47: 23-26.
100. LANDSIEDL, A. 1942. "Ein Beitrag zur Epidemiologie und Symptomatologie der Tularamie." Der. Dtsch. Militararzt. 7: 644-647.
101. KARADENIZLI, A. et al. 2005. Outbreak of tularaemia in Golcuk, Turkey in 2005: report of 5 cases and an overview of the literature from Turkey. Scand. J. Infect. Dis. 37: 712-716.
102. PARKER, R.R. 1934. Recent studies of tick-borne disease made at the United States Public Health Service laboratory at Hamilton, Montana. 5th Pac. Sci. Cong., 1934 3367-3374.
103. MCCARTHY, V.P. & M.D. MURPHY. 1990. Lawnmower tularemia. Pediatr. Infect. Dis J. 9: 298-300.
104. TARNVIK, A. & L. BERGLUND. 2003. Tularaemia. Eur. Respir. J. 21: 361-373.
105. DIENST, J.F.T. 1963. Tularemia - a perusal of three hundred thirty-nine cases. J. Louisiana State Med. Soc. 115: 114-127.
106. TIGERTT, W.D. 1962. Soviet viable Pasteurella tularensis vaccines. A review of selected articles. Bacteriol. Rev. 26: 354-373.
107. FAIBICH, M.M. 1959. [On the problem of the increase of immunogenic properties of live vaccine against tularemia.]. Z. Mikrobiol. Epidemiol. Immunobiol. 30: 20-24.
108. POLLITZER, R. 1967. History and incidence of tularemia in the Soviet Union. A review. The Institute of Contemporary Russian Studies, Fordham University, New York.
109. BURKE, D.S. 1977. Immunization against tularemia: analysis of the effectiveness of live Francisella tularensis vaccine in prevention of laboratory-acquired tularemia. J. Infect. Dis. 135: 55-60.
110. CONLAN, J.W. 2004. Vaccines against Francisella tularensis- past, present and future. Expert Rev. Vaccines. 3: 307-314.
111. PIOTROVSKAIA, S.A. 1958. [Certain indices of immunity in children vaccinated against tularemia.]. Z. Mikrobiol. Epidemiol. Immunobiol. 29: 129.
112. CONLAN, J.W. et al. 2002. Mice vaccinated with the O-antigen of Francisella tularensis LVS lipopolysaccharide conjugated to bovine serum albumin develop varying degrees of protective immunity against systemic or aerosol challenge with virulent type A and type B strains of the pathogen. Vaccine. 20: 3465-3471.
113. ERICSSON, M. et al. 1994. Persistence of cell-mediated immunity and decline of humoral immunity to the intracellular bacterium Francisella tularensis 25 years after natural infection. J. Infect. Dis. 170: 110-114.
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Language: | English.
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Document Type: | Original Article.
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Journal Subset: | Clinical Medicine. Behavioral & Social Sciences. Life Sciences. Physical Science & Engineering.
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ISSN: | 0077-8923
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NLM Journal Code: | 5nm, 7506858
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