Four cases of nafcillin-associated acute interstitial nephritis in one institution.
Hoppes, Tobin; Prikis, Marios *; Segal, Alan
[Article]
Nature Clinical Practice Nephrology.
3(8):456-461, August 2007.
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Background: Over the course of 1 year, four patients in a single institution developed acute kidney injury most likely secondary to nafcillin-associated acute interstitial nephritis, indicating that this complication might not be as rare as is commonly believed. The main case presented here is that of a 73-year-old man with a history of chronic low back pain who presented with worsening back pain, as well as nausea, vomiting and volume depletion. Imaging studies revealed a soft tissue abscess in the left psoas major muscle.
Investigations: Physical examination, complete urine analysis, blood and urine cultures, measurement of peripheral eosinophil and plasma creatinine levels, and renal ultrasound.
Diagnosis: Nafcillin-associated acute interstitial nephritis.
Management: Discontinuation of nafcillin and provision of supportive care.
Copyright (C) 2007 Nature Publishing Group