Clinical Presentation of Extramammary Paget Disease of the Axilla in a Male Patient.
Deutsch, Michael 1; Yeh, Janet 1; Grunes, Dianne 2; Horowitz, Elizabeth 1; Johnson, Elaheh 1; Joseph, Kathie-Ann 1,*
[Report] Clinical Breast Cancer. 15(2):e159-e161, April 2015.

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Clinical Practice Points:

* Extramammary Paget disease is a rare condition most often found in the penile and vulvar regions but is not necessarily limited to these locations.

* The nonspecific symptoms and visual presentation can mimic a variety of other dermatological conditions, often delaying diagnosis.

* Immunohistochemical staining for markers including cytokeratin 7 are becoming increasingly important in making the diagnosis.

* The current mainstay of therapy is surgical excision with wide margins.

* Multiple new modalities are being tested to reduce the need for operative definitive therapy, potentially reducing morbidity.

(C) 2015Elsevier, Inc.