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Learning Objectives: After reading this article, the participant should be able to: 1. Understand the theory and principles behind successful avascular fat transfer; 2. Apply these principles into techniques that yield safe and successful fat grafting operations; 3. Identify the well-established indications and limitations of the various fat grafting operations as well as the indications that require additional clinical and translational research.

Summary: In this article, the authors summarize the established principles and techniques of fat grafting, discuss debated topics, and present both the well-established and the novel clinical applications of fat grafting.

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