Age-related CD8 T Cell Clonal Expansions Constrict CD8 T Cell Repertoire and Have the Potential to Impair Immune Defense: J. LeMaoult's present address is Laboratoire d'Immuno de Transplantation, CEA/SRHI, Hopital St. Louis, 1 Ave. C., Vellefaux, 75010 Paris, France.: J.A. Guevara-Patino's present address is Dept. of Surgery, Pritzker Medical School, University of Chicago, 924 E. 57th Ave., Chicago, IL 60637.: B.M. Metzner's present address is Medigene, Inc., Lochhamer Str. 11, 85152 Martinsried, Germany.: Abbreviations used in this paper: ATX, adult thymectomy; CTLp, TEL precursors; FCM, flow cytofluorometry; pMHC, peptide-MHC; TCE, T cell clonal expansion(s).
Messaoudi, Ilhem; LeMaoult, Joe[Combining Diaeresis]l; Guevara-Patino, Jose A.; Metzner, Beatrix M.; Nikolich-Z[Combining Caron]ugich, Janko
Journal of Experimental Medicine.
200(10):1347-1358, November 15, 2004.