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Sensory neuropathy with low-dose pyridoxine. Parry, Gareth J. MB, FRACP; Bredesen, Dale E. MD [Miscellaneous] Neurology. 35(10):1466-1468, October 1985.
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Article abstract: We describe 16 patients with neuropathy associated with pyridoxine abuse. The clinical picture of a pure sensory central-peripheral distal axonopathy was consistent. Pyridoxine dose was 0.2 to 5 g/d, and duration of consumption before symptoms was inversely proportional to the daily intake. In all patients with adequate follow-up, improvement followed discontinuation of pyridoxine. The ready availability of up to 1-gram tablets makes it likely that this neuropathy will continue to be seen.
(C)1985 American Academy of Neurology