Neurotoxicity of Novel Water-Soluble Contrast Media for Intrathecal Application.
GONSETTE, R. E. MD; BRUCHER, J. M. MD
[Miscellaneous] Investigative Radiology. 15 Supplement 6:S254-S259, November/December 1980.

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Novel nonionic contrast media were tested by injection into the subarachnoid space of the anterior fossae of guinea pigs, followed by EEG recording and histologic examination. Iopamidol was found to be more epileptogenic than metriza-mide and P-297.

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